Cancer Protocols
Updated October 14, 2014
The College of American Pathologists (CAP) has produced the new Template for Reporting Results of Biomarker Testing of Specimens from Patients with Melanoma. This template was developed to respond to pathologist user feedback about timing of reporting and structural consistency of ancillary studies data elements found in the CAP Cancer Protocols and to provide educational materials to help pathologists better understand emerging biomarkers. The development of this template has been a collaborative effort between CAP, AMP, ASCO, CDC, AJCC and many other participating organizations.
The Cancer Biomarker Reporting Committee (CBRC) welcomes your feedback on this new biomarker reporting template. Thank you in advance for taking the time to review and submit your response.
The information, data, and draft recommendations and summaries provided by the College of American Pathologists are presented for informational and public feedback purposes only. These draft materials should not be stored, adapted, or redistributed in any manner and will be removed November 14, 2014.
The CAP produces Cancer Protocols as a resource to pathologists to aid in effectively reporting surgical pathology findings necessary to provide quality patient care. The protocols consist of cancer case summaries accompanied by background documentation. The background documentation includes detailed outlines, explanatory notes, and references.
The Cancer Biomarker Reporting Templates are produced to establish reporting guidance for commonly ordered biomarkers, create stand-alone reporting templates, and improve consistency and completeness of results reporting to assist tumor registrars and others involved in data collection, exchange, and surveillance. These reporting templates are intended to encompass all important data elements for routinely assessed tumor markers and are designed to be incorporated into electronic reporting systems. Completion of the template is the responsibility of the laboratory performing the biomarker testing and/or providing the interpretation.
Use of the Cancer Biomarker Reporting Templates is entirely optional and is currently not a requirement for laboratory accreditation.
| Protocols | Download | |||
| Breast | ||||
| DCIS – Breast Posted: December 18, 2013 |
PDF (601 KB) |
Word (461 KB) |
2012 Version (PDF, 357 KB) |
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| Invasive Breast Posted: December 18, 2013 |
PDF (2 MB) |
Word (1 MB) |
2012 Version (PDF, 1.2 MB) |
Work Aid (Word, 137 KB) |
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PDF (422 KB) |
Word (241 KB) |
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| Central Nervous System |
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| Brain/Spinal Cord Posted: January 30, 2013 |
PDF (217 KB) |
Word (187 KB) |
2012 Version (PDF, 217 KB) |
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| Endocrine |
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| Adrenal Gland Posted: October 1, 2013 |
PDF (858 KB) |
Word (647 KB) |
2012 Version (PDF, 815 KB) |
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| Appendix NET Posted: October 1, 2013 |
PDF (372 KB) |
Word (262 KB) |
2012 Version (PDF, 513 KB) |
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| Colon NET Posted: October 1, 2013 |
PDF (382 KB) |
Word (266 KB) |
2012 Version (PDF, 512 KB) |
|
| Pancreas (Endocrine) Posted: October 1, 2013 |
PDF (2 MB) |
Word (1.9 MB) |
2012 Version (PDF, 1.4 MB) |
|
| Small Intestine NET Posted: October 1, 2013 |
PDF (395 KB) |
Word (270 KB) |
2012 Version (PDF, 522 KB) |
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| Stomach NET Posted: October 1, 2013 |
PDF (175 KB) |
Word (71 KB) |
2012 Version (PDF, 81 KB) |
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| Thyroid Posted: August 12, 2014 |
PDF (545 KB) |
Word (743 KB) |
2012 Version (PDF, 2.4 KB) |
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| Gastrointestinal |
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| Ampulla of Vater Posted: October 1, 2013 |
PDF (739 KB) |
Word (974 KB) |
2012 Version (PDF, 722 KB) |
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| Anus Posted: October 1, 2013 |
PDF (778 KB) |
Word (1.1 MB) |
2012 Version (PDF, 766 KB) |
|
| Appendix Posted: October 1, 2013 |
PDF (173 KB) |
Word (77 KB) |
2012 Version (PDF, 170 KB) |
|
| Colon and Rectum Posted: October 1, 2013 |
PDF (2.5 MB) |
Word (2.2 MB) |
2012 Version (PDF, 1.8 MB) |
Work Aid (Word, 125 KB) |
|
PDF (1.6 MB) |
Word (73 kB) |
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| Distal Extrahepatic Bile Ducts Posted: October 1, 2013 |
PDF (457 KB) |
Word (338 KB) |
2012 Version (PDF, 250 KB) |
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| Esophagus Posted: October 1, 2013 |
PDF (4.5 MB) |
Word 4.1 MB) |
2012 Version (PDF, 7 MB) |
Work Aid (Word, 122 KB) |
| Gallbladder Posted: October 1, 2013 |
PDF (967 KB) |
Word (853 MB) |
2012 Version (PDF, 749 KB) |
|
| GIST Posted: October 1, 2013 |
PDF (1.6 KB) |
Word (604 KB) |
2012 Version (PDF, 1.6 KB) |
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| Hepatocellular Carcinoma Posted: June 15, 2012 |
PDF (654 KB) |
Word (509 KB) |
2011 Version (PDF, 652 KB) |
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| Intrahepatic Bile Ducts Posted: October 1, 2013 |
PDF 664 KB) |
Word (509 KB) |
2012 Version (PDF, 834 KB) |
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| Pancreas (Exocrine) Posted: October 1, 2013 |
PDF (1.5 MB) |
Word (1.9 MB) |
2012 Version (PDF, 1.4 MB) |
|
| Perihilar Bile Ducts Posted: October 1, 2013 |
PDF (468 KB) |
Word (345 KB) |
2012 Version (PDF, 448 KB) |
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| Small Intestine Posted: October 1, 2013 |
PDF (1.3 MB) |
Word (1.2 MB) |
2012 Version (PDF, 1 MB) |
|
| Stomach Posted: June 11, 2013 |
PDF 1.4 KB) |
Word (2.3 MB) |
2013 Version (PDF, 718 KB) |
|
|
PDF (0.97 MB) |
Word (57.5 kB) |
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| Genitourinary |
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| Kidney Posted: October 1, 2013 |
PDF (1.5 MB) |
Word (408 KB) |
2012 Version (PDF, 1.4 MB) |
Work Aid (Word, 123 KB) |
| Penis Posted: October 1, 2013 |
PDF (5.1 MB) |
Word (4.1 MB) |
2011 Version (PDF, 227 KB) |
|
| Prostate Gland Posted: June 15, 2012 |
PDF (542 KB) |
Word (284 KB) |
2011 Version (PDF, 542 KB) |
Work Aid (Word, 112 KB) |
| Testis Posted: October 1, 2013 |
PDF (760 KB) |
Word (693 KB) |
2012 Version (PDF, 729 KB) |
|
| Ureter, Renal Pelvis Posted: October 1, 2013 |
PDF (722 KB) |
Word (306 KB) |
2012 Version (PDF, 708 KB) |
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| Urethra Posted: October 1, 2013 |
PDF (183 KB) |
Word (100 KB) |
2012 Version (PDF, 179 KB) |
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| Urinary Bladder Posted: October 1, 2013 |
PDF (215 KB) |
Word (115 KB) |
2012 Version (PDF, 216 KB) |
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| Gynecologic |
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| Endometrium Posted: December 18, 2013 |
PDF (688 KB) |
Word (323 KB) |
2012 Version (PDF, 679 KB) |
Work Aid (Word, 126 KB) |
| Fallopian Tube Posted: October 1, 2013 |
PDF (1.8 MB) |
Word (856 KB) |
2012 Version (PDF, 1.7 MB) |
|
| Ovary Posted: October 1, 2013 |
PDF (1.9 MB) |
Word (878 KB) |
2012 Version (PDF, 1.8 MB) |
|
| Trophoblastic Tumors Posted: October 1, 2013 |
PDF (188 KB) |
Word (65 KB) |
2012 Version (PDF, 181 KB) |
|
| Uterine Cervix Posted: December 18, 2013 |
PDF (209 KB) |
Word (127 KB) |
2012 Version (PDF, 202 KB) |
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| Uterine Sarcoma Posted: December 18, 2013 |
PDF (213 KB) |
Word (246 KB) |
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| Vagina Posted: December 18, 2013 |
PDF (161 KB) |
Word (83 KB) |
2011 Version (PDF, 152 KB) |
|
| Vulva Posted: June 15, 2012 |
PDF (172 KB) |
Word (98 KB) |
2011 Version (PDF, 77 KB) |
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| Head and Neck |
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| Larynx Posted: October 1, 2013 |
PDF (1.1 MB) |
Word (1.2 MB) |
2012 Version (PDF, 1.2 MB) |
|
| Lip and Oral Cavity Posted: October 1, 2013 |
PDF (2.5 MB) |
Word (1.7 MB) |
2012 Version (PDF, 2.3 MB) |
|
| Major Salivary Glands Posted: October 1, 2013 |
PDF (818 KB) |
Word (610 KB) |
2012 Version (PDF, 771 KB) |
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| Nasal Cavity and Paranasal Sinuses Posted: October 1, 2013 |
PDF (528 KB) |
Word (511 KB) |
2012 Version (PDF, 488 KB) |
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| Pharynx Posted: October 1, 2013 |
PDF (2.1 MB) |
Word (2.2 MB) |
2012 Version (PDF, 2 MB) |
|
| Hematologic |
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| Bone Marrow Posted: June 15, 2012 |
PDF (185 KB) |
Word (92 KB) |
2011 Version (PDF, 129 KB) |
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| Hodgkin Lymphoma Posted: October 1, 2013 |
PDF (165 KB) |
Word (90 KB) |
2012 Version (PDF, 165 KB) |
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| Non-Hodgkin Lymphoma Posted: October 1, 2013 |
PDF (264 KB) |
Word (132 KB) |
2010 Version (PDF, 264 KB) |
Work Aid (Word, 102 KB) |
| Ocular Adnexal Lymphoma Posted: June 15, 2012 |
PDF (181 KB) |
Word (94 KB) |
2010 Version (PDF, 134 KB) |
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| Ophthalmic |
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| Retinoblastoma Posted: October 1, 2013 |
PDF (475 KB) |
Word (259 KB) |
2012 Version (PDF, 475 KB) |
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| Uveal Melanoma Posted: October 1, 2013 |
PDF (508 KB) |
Word (283 KB) |
2012 Version (PDF, 508 KB) |
|
| Pediatric |
||||
| Extragonadal Germ Cell Posted June 15, 2012 |
PDF (278 KB) |
Word (217 KB) |
2011 Version (134 KB) |
|
| Hepatoblastoma Posted: October 1, 2013 |
PDF (212 KB) |
Word (82 KB) |
2012 Version (PDF, 212 KB) |
|
| Neuroblastoma Posted: June 15, 2012 |
PDF (238 KB) |
Word (165 KB) |
2012 Version (PDF, 238 KB) |
|
| PNET/Ewing Sarcoma Posted: June 15, 2012 |
PDF (401 KB) |
Word (519 KB) |
2011 Version (PDF, 410 KB) |
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| Rhabdomyosarcoma Posted: June 15, 2012 |
PDF (203 KB) |
Word (104 KB) |
2011 Version (PDF, 203 KB) |
|
| Wilms Tumor Posted: June 15, 2012 |
PDF (182 KB) |
Word (97 KB) |
2011 Version (PDF, 98 KB) |
|
| Skin |
||||
| Melanoma Posted: October 1, 2013 |
PDF (653 KB) |
Word (707 KB) |
2012 Version (622 KB) |
Work Aid (Word, 115 KB) |
| Merkel Cell Carcinoma Posted: June 15, 2012 |
PDF (545 KB) |
Word (543 KB) |
2011 Version (107 KB) |
|
| Squamous Cell Carcinoma Posted: October 1, 2013 |
PDF (168 KB) |
Word (84 KB) |
2012 Version (159 KB) |
|
| Thorax |
||||
| Heart Posted: June 15, 2012 |
PDF (114 KB) |
Word (59 KB) |
2012 Version (PDF, 114 KB) |
|
| Lung Posted: October 1, 2013 |
PDF (1.4 MB) |
Word (363 KB) |
2012 Version (1.3 MB) |
Work Aid (Word, 137 KB) |
|
PDF (1.3 MB) |
Word (66 KB) |
||
| Pleural Mesothelioma Posted: June 15, 2012 |
PDF (135 KB) |
Word (78 KB) |
2011 Version (44 KB) |
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| Thymoma and Thymic Carcinoma Posted: June 15, 2012 |
PDF (133 KB) |
Word (72 KB) |
2011 Version (PDF, 133 KB) |
|
| Other |
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| Bone Posted: October 1, 2013 |
PDF (289 KB) |
Word (238 KB) |
2012 Version (266 KB) |
|
| Peritoneum Posted: October 1, 2013 |
PDF (115 KB) |
Word (63 KB) |
2011 Version (PDF, 113 KB) |
|
| Soft Tissue Posted: October 1, 2013 |
PDF (243 KB) |
Word (183 KB) |
2012 version (233 KB) |
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